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Question:

A disease caused by an autosomal primary non-disjunction is

Sickle cell anemia

Down's syndrome

Turner's syndrome

Klinefelter's syndrome

Solution:

The correct option is B Down's syndrome. Down's syndrome is caused due to the trisomy of 21 chromosome which is an autosome. It is mainly caused due to the non-disjunction of the chromosomes. Non-disjunction is the condition when the sister chromatids fail to separate during the cell division. So, the correct answer is option B.