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Question:

Conversion of glucose to glucose-6-phosphate, the first irreversible reaction of glycolysis, is catalyzed by?

Aldolase

Enolase

Phosphofructokinase

Hexokinase

Solution:

Correct option is Hexokinase. Hexokinase catalyzes the conversion of Glucose to Glucose-6-phosphate. It is the first step of the activation phase of glycolysis. So, the correct answer is 'Hexokinase'