After entry of sperm but before fertilization
After fertilization
Simultaneously with first cleavage
Before entry of sperm into ovum
Correct option is A. After entry of sperm but before fertilization
Correct Option: A
Explanation:During fertilization, the acrosome's secretion helps the sperm to enter into the cytoplasm of the ovum.This induces the completion of the second meiotic division of the secondary oocyte.The second meiotic division results in the formation of a second polar body and a haploid ovum.Then the haploid nucleus of the sperms and that of the ovum fuse together to form a diploid zygote.Thus, the correct answer is option A.