Grafted kidney may be rejected in a patient due to Innate immune response, Humoral immune response, Cell-mediated immune response, Passive immune response

In graft rejection, grafts of a kidney, heart, lung, liver, etc. from one human to another always (unless donated by an identical twin) are seen by the recipient's immune system as antigenic (foreign) and elicit an immune response. If unchecked, this response will eventually lead to the destruction of the graft. Both CD4+ and CD8+ T cells participate in graft rejection. T cells (lymphocytes) bind to the surface of other cells that display the antigen and trigger a response.So, the correct answer is option C.