Interspecific hybridization is the mating of _________.

Interspecific hybridization refers to a cross between two individuals of two different species or different genera to bring their characters together in the hybrid progeny. Mule is produced by interspecific hybridization. A cross between superior males and females of different breeds refers to cross-breeding while that between animals within the same breed without having common ancestors is called outcrossing. Therefore, the correct answer is option D.