The first bioherbicide developed in 1981 was based on Phytophthora palmivora, Phytophthora infestans, Bacillus thuringiensis, Azadirachta indica

The first bioherbicide is device, which is a mycoherbicide, based on fungus Phytophthora palmivora. It is being used since 1981 to control Morrenia odorata (milkweed vines) in citrus orchards.