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Question:

The reason for "drug induced poisoning" is: binding at the allosteric sites of the enzyme; binding irreversibly to the active site of the enzyme; binding reversibly at the active site of the enzyme; bringing conformational change in the binding site of the enzyme

binding at the allosteric sites of the enzyme

bringing conformational change in the binding site of the enzyme

binding irreversibly to the active site of the enzyme

binding reversibly at the active site of the enzyme

Solution:

The reason for "drug induced poisoning" is the binding of drug, irreversibly, to the active site of the enzyme. If this happens, then the body degenerates the enzyme and releases a new enzyme.