The tendency of population to remain in genetic equilibrium may be disturbed by _________.

The Hardy-Weinberg principle provides the mathematical framework for genetic equilibrium. Genetic equilibrium describes the condition of an allele or genotype in a gene pool (such as a population) where the frequency does not change from generation to generation. Genetic equilibrium describes a theoretical state that is the basis for determining whether and in what ways populations may deviate from it. The Hardy-Weinberg equilibrium can be disturbed by a number of forces, including mutations, natural selection, non-random mating, genetic drift, and gene flow (immigration, emigration, or migration). Hence, the lack of random mating will lead to disturbance in genetic equilibrium.