Three of the following statements about enzymes are correct and one is wrong. Which one is wrong?

Most enzymes are proteins, although a few are catalytic RNA molecules. Enzymes increase the rate of a reaction by lowering its activation energy. Enzymes are not consumed in chemical reactions, nor do they alter the equilibrium of a reaction. Enzyme activity can be affected by other molecules: inhibitors are molecules that decrease enzyme activity, and activators are molecules that increase activity. An enzyme's activity decreases markedly outside its optimal temperature and pH.