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Question:

What happens when anisole is treated with CH3Cl/anhydrous AlCl3?

Solution:

When anisole is treated with CH3Cl in the presence of anhydrous AlCl3, a mixture of ortho and para methyl anisole is produced. Anisole undergoes Friedel-Crafts alkylation reaction with an alkyl halide in the presence of Lewis acid AlCl3 as a catalyst.