devarshi-dt-logo

Question:

When a cell has a stalled DNA replication fork, which checkpoint should be predominantly activated?

G1/S

M

Both G2M and M

G2/M

Solution:

When the DNA replication in the S-phase is stalled, the DNA replication and synthesis is not complete. This causes the activation of the G2/M checkpoint which does not allow the cell to enter the G2 and the M phase until the replication is complete. So, the correct answer is G2/M.