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Question:

Which of the following is true for nucleolus?

Larger nucleoli are present in dividing cells.

It is a site for active ribosomal RNA synthesis.

It is a membrane-bound structure.

It takes part in spindle formation.

Solution:

Nucleolus is the spherical structure present in the nucleoplasm. It is the site of ribosomal RNA (rRNA) synthesis. The nucleolus is not membrane-bound; it is a region within the nucleus where rRNA is transcribed and ribosomal subunits are assembled. Larger nucleoli are often observed in cells that are actively synthesizing proteins and thus require a high number of ribosomes. The spindle formation is carried out by centrosomes and microtubules, not the nucleolus.