Cadmium - Minamata disease
Arsenic - Black foot disease
Mercury - Skeletal fluorosis
Flouride - Itai-itai
Blackfoot disease or arsenicosis is caused by exposure over a period of time to arsenic in drinking water. It may also cause due to the intake of arsenic via food or air. It is an endemic peripheral vascular disease confined to the southwestern coast of Taiwan. Itai-Itai is caused due to Cadmium. Minamata disease is caused due to Mercury. Skeletal fluorosis is caused due to Flouride. So, the correct answer is option B.