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Question:

Which one of the following statements is correct, with reference to enzymes?

Apoenzyme=Holoenzyme+Coenzyme

Coenzyme=Apoenzyme+Holoenzyme

Holoenzymes=Coenzyme+Co-factor

Holoenzyme=Apoenzyme+Coenzyme

Solution:

Holoenzyme is the active form of the enzyme. It is made of 2 components called the apoenzyme and coenzyme. A cofactor can also be a called as a coenzyme if it is an organic molecule. The apoprotein itself is inactive. On binding with the cofactor, it gets activated resulting in the formation of a holoenzyme that is functional. Thus the correct answer is option D. The correct equation is Holoenzyme = Apoenzyme + Coenzyme