Coenzymes increase the catalytic activity of enzyme
Catalyst does not initiate any reaction
The value of equilibrium constant is changed in the presence of a catalyst in the reaction at equilibrium
Enzymes catalyse mainly bio-chemical reactions
The value of equilibrium constant is not changed in the presence of a catalyst in the reaction at equilibrium. The catalyst increases the rate of forward and reverse reaction to the same extent. It does not affect the value of the equilibrium constant.