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Question:

Which two antibodies showed an ability recently to neutralize the virus of the epidemic of Middle-East Respiratory Syndrome (MERS)?

REGN3048

REGN3051

Both (a) and (b)

None of these

Solution:

The correct option is C Both (a) and (b). Generation of two fully human antibodies (REGN3051 and REGN3048), which bind to the MERS-CoV RBD, block the interaction of the S protein with its cellular receptor DPP4, and very potently neutralize MERS-CoV infectivity.